I am never without PBG. I started having some pretty severe spasms in my ribs that were crippling due to a fall I had. I was headed out of state and it started with the knot like spasms. I had my PBG with me and after one dose it calmed it right down. I took a 2nd dose about an hour later and no more spasms. I also used this when I broke my shoulder and nothing else worked. I was able to sleep after using PBG.